Caris MI Profile

Caris MI Profile is an advanced tumor profiling test that analyzes DNA, RNA, and protein expression to guide precision oncology treatment.

Caris MI Profile – Comprehensive Molecular Profiling for Solid Tumors

Optimize treatment with deep molecular insights.

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Comprehensive Analysis: DNA, RNA, and IHC profiling in a single test

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Actionable Insights: Identifies targeted therapies, immunotherapy options, and clinical trials

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High Sensitivity: Detects all classes of molecular alterations (mutations, fusions, amplifications, splice variants)

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Clinical Utility: Helps oncologists tailor treatment plans based on tumor biology

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Guideline-Based: Incorporates biomarkers referenced in NCCN and ESMO guidelines

What is the Caris MI Test?

Caris MI Profile provides a full molecular characterization of solid tumors using advanced sequencing technologies.
It analyzes more than 700 DNA genes, 20,000 RNA transcripts, and dozens of proteins using immunohistochemistry (IHC).
The goal is to match patients with the most effective therapies based on the genetic and molecular features of their tumor.

Important To Know
Test Name: Breast Cancer Index (BCI) Performing Laboratory: Biotheranostics, a Hologic Company Sample Type: FFPE breast tumor tissue Turnaround Time: 7–10 business days Contact Information: Phone: 03-5541464 Email: contact@progenetics.co.il Company: Progenetics – Advancing Personalized Medicine

The Testing Process

01
Tissue Submission

Tumor sample is submitted (from biopsy or surgical resection)

02
Multi-Omic Analysis

DNA and RNA sequencing + IHC and other biomarker testing

03
Bioinformatics Reporting

Results interpreted via AI-enhanced platform with expert review

04
Comprehensive Report

Delivered to the treating physician with actionable recommendations

Who Should Consider the Test?

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Patients with advanced, metastatic, or recurrent solid tumors

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Individuals with rare cancers or tumors of unknown origin

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Patients who have exhausted standard treatments and need guidance on next steps

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Oncologists seeking data to support enrollment in clinical trials

Clinical and scientific information

  • Reporting: Includes therapeutic matches, resistance markers, clinical trials, and FDA-approved options
  • Accreditation: Performed in CAP- and CLIA-certified laboratories
  • Reporting: Includes therapeutic matches, resistance markers, clinical trials, and FDA-approved options
  • Accreditation: Performed in CAP- and CLIA-certified laboratories

FAQ

It integrates multi-omic analysis (DNA, RNA, protein) to deliver a deeper, more actionable profile.

Coverage varies. Many private and public plans reimburse the test. Contact us for verification.

Formalin-fixed, paraffin-embedded (FFPE) tumor tissue block or slides from prior biopsy or surgery.